Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135837 | 0.93 | BRD4 (0.65) | BRD4 | |
| SCHEMBL20135820 | 0.82 | BRD4 (0.51) | BRD4 | |
| SCHEMBL20135880 | 0.80 | BRD4 (0.49) | BRD4 | |
| SCHEMBL15540566 | 0.79 | BRD4 (0.86) | BRD4 | |
| SCHEMBL20135841 | 0.77 | BRD4 (0.53) | BRD4 | |
| SCHEMBL20135876 | 0.76 | BRD4 (0.49) | BRD4 | |
| SCHEMBL20135817 | 0.76 | BRD4 (0.58) | BRD4 | |
| SCHEMBL20135878 | 0.76 | BRD4 (0.53) | BRD4 | |
| SCHEMBL20135818 | 0.75 | BRD4 (0.64) | BRD4 | |
| SCHEMBL20135877 | 0.75 | BRD4 (0.62) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858990-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC (US) | 2018-05-16 | — | — | EP | claimed |