Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538778 | 0.86 | BRD4 (0.62) | BRD4 | |
| SCHEMBL15539865 | 0.85 | BRD4 (0.54) | BRD4SCN9A | |
| SCHEMBL15558311 | 0.83 | BRD4 (0.70) | BRD4 | |
| SCHEMBL15538643 | 0.82 | BRD4 (0.63) | BRD4 | |
| SCHEMBL15541470 | 0.81 | BRD4 (0.68) | BRD4 | |
| SCHEMBL15069344 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL29745704 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15538589 | 0.78 | BRD4 (0.58) | BRD4SCN9A | |
| SCHEMBL15539254 | 0.78 | BRD4 (0.58) | BRD4SCN9A | |
| SCHEMBL15540258 | 0.77 | BRD4 (0.56) | BRD4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858990-B1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC (US) | 2018-05-16 | — | — | EP | disclosed |