Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536629 | 0.88 | CPN1 (0.53) | CPN1CPB2GBA1SLC6A4SLC6A2 | |
| SCHEMBL27832973 | 0.85 | CPN1 (0.45) | CPN1CPB2GBA1OPRD1CACNA2D1 | |
| SCHEMBL8129250 | 0.80 | CPN1 (0.50) | CPN1CPB2GBA1SLC6A3OPRD1 | |
| SCHEMBL31381427 | 0.77 | CPN1 (0.45) | CPN1CPB2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7875085 | 0.77 | GBA1 (0.47) | GBA1SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL8969997 | 0.77 | GBA1 (0.47) | GBA1SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL4156782 | 0.77 | EPHX1 (0.43) | CPN1CPB2GBA1SLC6A4SLC6A2 | |
| SCHEMBL4156781 | 0.77 | EPHX1 (0.43) | CPN1CPB2GBA1SLC6A4SLC6A2 | |
| SCHEMBL22610142 | 0.75 | MFN2 (0.43) | — | |
| SCHEMBL22610143 | 0.75 | MFN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |