SCHEMBL20138696

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20154249	0.90	CYP1A2 (0.40)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2
	SCHEMBL20138688	0.85	CYP1A2 (0.47)	CYP1A2CYP2C9CYP2C19CYP3A4TSHR
	SCHEMBL20138702	0.84	CYP1A2 (0.38)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2
	SCHEMBL20138714	0.83	AR (0.36)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2
	SCHEMBL20159244	0.83	CYP1A2 (0.36)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2
	SCHEMBL20138690	0.78	PSEN1 (0.51)	CYP1A2CYP2C9CYP2C19CYP3A4EGFR
	SCHEMBL20138854	0.75	KDM4E (0.38)	CYP1A2CYP2C9CYP2C19SLC6A4SLC6A2
	SCHEMBL20159678	0.75	CYP1A2 (0.44)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2
	SCHEMBL20143018	0.70	EPAS1 (0.37)	—
	SCHEMBL5561960	0.70	CYP1A2 (0.44)	CYP1A2CYP2C9CYP2C19SLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.