SCHEMBL20138713

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20143001	0.89	HTR2A (0.38)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20142958	0.88	EGFR (0.38)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20142969	0.86	BRD9 (0.41)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20142941	0.83	HTR2A (0.37)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20138686	0.83	SOS1 (0.36)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20142980	0.82	HTR2A (0.36)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20138791	0.82	KDR (0.41)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20154256	0.82	SOS1 (0.36)	SOS1HTR2ASLC6A4KCNH2KDR
	SCHEMBL20138671	0.82	EPAS1 (0.36)	PPARG
	SCHEMBL20142946	0.78	RAF1 (0.36)	SOS1HTR2ASLC6A4KCNH2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.