⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138844 | 1.00 | — | — | |
| SCHEMBL19745504 | 0.82 | — | — | |
| SCHEMBL19745502 | 0.82 | — | — | |
| SCHEMBL28197577 | 0.77 | — | — | |
| SCHEMBL29290878 | 0.75 | — | — | |
| SCHEMBL18513472 | 0.73 | — | — | |
| SCHEMBL2154222 | 0.69 | — | — | |
| SCHEMBL29768627 | 0.64 | — | — | |
| SCHEMBL28299873 | 0.64 | — | — | |
| SCHEMBL4598893 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908587-A1 | METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2021-11-17 | — | — | EP | disclosed |
| CN-113661166-A | Process for the synthesis of diazabicyclo [6.2.0] decane-related compounds | 卫材R&D管理有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2020146568-A1 | METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-07-16 | — | — | WO | disclosed |
| EP-3538158-A1 | TREATMENT FOR FIBROSIS | Galmed Research and Development Ltd. (IL) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018087599-A1 | TREATMENT FOR FIBROSIS | GALMED RESEARCH AND DEVELOPMENT LTD. (IL) | 2018-05-17 | — | — | WO | disclosed |
| CN-106999593-A | Sai Nikeweiluo combination treatments for treatment of fibrosis | 妥必徕疗治公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-105263498-A | Cenicriviroc compositions and methods of making and using the same | TOBIRA THERAPEUTICS INC | 2016-01-20 | — | — | CN | disclosed |