Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.52 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.52 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159032 | 0.87 | MTOR (0.57) | MTORRPTORMLST8SCD5HTR7 | |
| SCHEMBL20159033 | 0.87 | MTOR (0.57) | MTORRPTORMLST8SCD5HTR7 | |
| SCHEMBL20159083 | 0.87 | MTOR (0.57) | MTORRPTORMLST8SCD5HTR7 | |
| SCHEMBL20140150 | 0.86 | MTOR (0.57) | MTORRPTORMLST8SCD5HTR7 | |
| Trifluoroacetic Acid SCHEMBL20142573 | 0.83 | MTOR (0.55) | MTORRPTORMLST8SCD5CHRM4 | |
| Trifluoroacetic Acid SCHEMBL20141728 | 0.83 | MTOR (0.55) | MTORRPTORMLST8SCD5CHRM4 | |
| SCHEMBL20139265 | 0.81 | MTOR (0.52) | MTORRPTORMLST8SCD5HTR7 | |
| SCHEMBL20139828 | 0.80 | MTOR (0.49) | MTORRPTORMLST8SCD5NPC1 | |
| SCHEMBL20154262 | 0.79 | MTOR (0.48) | MTORRPTORMLST8SCD5CHRM4 | |
| SCHEMBL20139244 | 0.78 | MTOR (0.55) | MTORRPTORMLST8SCD5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |