Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156989 | 0.90 | GRM1 (0.41) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20157201 | 0.90 | GRM1 (0.41) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20140690 | 0.89 | GRM1 (0.43) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20139952 | 0.88 | GRM1 (0.43) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20140242 | 0.88 | MTOR (0.46) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20156992 | 0.80 | GRM1 (0.40) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20140102 | 0.80 | GRM1 (0.40) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20157202 | 0.80 | MTOR (0.43) | GRM1CHRM4CHRM2MTORRPTOR | |
| SCHEMBL20157203 | 0.79 | GRM1 (0.39) | GRM1DRD4DRD3CHRM4CHRM2 | |
| SCHEMBL20140204 | 0.78 | CHRM1 (0.48) | GRM1CHRM4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |