Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.54 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141157 | 1.00 | TSHR (0.62) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20140952 | 0.94 | NAMPT (0.54) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20140833 | 0.90 | MTOR (0.51) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20141103 | 0.90 | MYC (0.57) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20139958 | 0.85 | NAMPT (0.53) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20140604 | 0.84 | NAMPT (0.49) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL22187976 | 0.83 | MTOR (0.58) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL22186355 | 0.83 | MTOR (0.56) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20156949 | 0.83 | MTOR (0.54) | TSHRALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20141464 | 0.83 | MTOR (0.56) | TSHRALDH1A1MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |