Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139973 | 0.90 | MTOR (0.57) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140146 | 0.90 | KDM4E (0.53) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20139852 | 0.89 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141859 | 0.89 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20159127 | 0.84 | MTOR (0.62) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140097 | 0.83 | MTOR (0.51) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140641 | 0.83 | MTOR (0.54) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20157127 | 0.82 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20156883 | 0.81 | MTOR (0.46) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140388 | 0.80 | MTOR (0.47) | MTORRPTORMLST8DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |