Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 8/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.31 |
| ▸ | CDC25B | P30305 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139464 | 1.00 | SLC5A1 (0.38) | SLC5A1SLC5A2PTPN1CDC25BRXRA | |
| SCHEMBL20139387 | 0.93 | SLC5A1 (0.38) | SLC5A1SLC5A2PTPN1CDC25BTACR2 | |
| SCHEMBL20140115 | 0.93 | SLC5A1 (0.39) | SLC5A1SLC5A2PTPN1CDC25B | |
| SCHEMBL20141619 | 0.88 | SLC5A1 (0.43) | SLC5A1SLC5A2PTPN1CDC25BRXRA | |
| SCHEMBL20140047 | 0.84 | SLC5A1 (0.35) | SLC5A1SLC5A2PTPN1RXRATACR2 | |
| SCHEMBL20139724 | 0.83 | SLC5A1 (0.40) | SLC5A1SLC5A2PTPN1CDC25BTACR2 | |
| SCHEMBL20139983 | 0.83 | SLC5A1 (0.40) | SLC5A1SLC5A2PTPN1CDC25BTACR2 | |
| SCHEMBL20140226 | 0.83 | SLC5A1 (0.45) | SLC5A1SLC5A2PTPN1PTPN2PTPN11 | |
| SCHEMBL20140181 | 0.83 | SLC5A1 (0.41) | SLC5A1SLC5A2PTPN1 | |
| SCHEMBL20140244 | 0.83 | SLC5A1 (0.40) | SLC5A1SLC5A2PTPN1CDC25BTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |