Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129657 | 1.00 | MTOR (0.48) | MTORRPTORMLST8KDM4EBDKRB1 | |
| SCHEMBL22187910 | 0.93 | MTOR (0.45) | MTORRPTORMLST8KDM4EBDKRB1 | |
| SCHEMBL20129655 | 0.91 | MTOR (0.49) | MTORRPTORMLST8KDM4EADAM17 | |
| SCHEMBL20141096 | 0.91 | MTOR (0.49) | MTORRPTORMLST8KDM4EADAM17 | |
| SCHEMBL20141077 | 0.91 | MTOR (0.49) | MTORRPTORMLST8KDM4EADAM17 | |
| SCHEMBL20140888 | 0.91 | MTOR (0.49) | MTORRPTORMLST8KDM4EADAM17 | |
| SCHEMBL20133856 | 0.88 | MTOR (0.56) | MTORRPTORMLST8KDM4EBDKRB1 | |
| SCHEMBL20129666 | 0.85 | MTOR (0.62) | MTORRPTORMLST8KDM4EBDKRB1 | |
| SCHEMBL20129720 | 0.83 | MTOR (0.49) | MTORRPTORMLST8KDM4EBDKRB1 | |
| SCHEMBL20129726 | 0.83 | MTOR (0.49) | MTORRPTORMLST8KDM4EBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |