Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.68 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.68 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360325 | 1.00 | MTOR (0.68) | MTORRPTORMLST8ALDH1A1TSHR | |
| SCHEMBL21360385 | 0.96 | MTOR (0.72) | MTORRPTORMLST8ALDH1A1TSHR | |
| SCHEMBL20149902 | 0.96 | MTOR (0.72) | MTORRPTORMLST8ALDH1A1TSHR | |
| SCHEMBL22693146 | 0.96 | MTOR (0.73) | MTORRPTORMLST8NAMPT | |
| SCHEMBL21360330 | 0.94 | MTOR (0.65) | MTORRPTORMLST8NAMPT | |
| SCHEMBL21360366 | 0.93 | MTOR (0.65) | MTORRPTORMLST8NAMPTRECQL | |
| SCHEMBL20133739 | 0.92 | MTOR (0.78) | MTORRPTORMLST8ALDH1A1NAMPT | |
| SCHEMBL20150218 | 0.89 | MTOR (0.74) | MTORRPTORMLST8TSHRNAMPT | |
| SCHEMBL20133691 | 0.89 | MTOR (0.69) | MTORRPTORMLST8ALDH1A1TSHR | |
| SCHEMBL20133560 | 0.89 | MTOR (0.69) | MTORRPTORMLST8NAMPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |