Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139913 | 0.80 | DRD4 (0.47) | DRD4PHGDHDRD3KDM4EDRD2 | |
| SCHEMBL20140843 | 0.78 | MTOR (0.44) | DRD4PHGDHMTORRPTORMLST8 | |
| SCHEMBL20140782 | 0.72 | CHRM4 (0.44) | DRD4LMNAADAM17CHRM4MTOR | |
| SCHEMBL7519811 | 0.70 | CHRM4 (0.45) | DRD4CHRM4DRD3KDM4EDRD2 | |
| SCHEMBL8222584 | 0.70 | CHRM4 (0.46) | DRD4CHRM4DRD3KDM4EGRM2 | |
| SCHEMBL7520833 | 0.70 | CHRM4 (0.49) | DRD4ADAM17CHRM4DRD3KDM4E | |
| SCHEMBL30163903 | 0.70 | CHRM4 (0.46) | DRD4CHRM4DRD3KDM4EGRM2 | |
| SCHEMBL20139884 | 0.70 | BDKRB1 (0.47) | DRD4DPP4ADAM17CHRM4MTOR | |
| SCHEMBL15831837 | 0.68 | FFAR4 (0.54) | LMNATSHRHSD17B10L3MBTL1HTT | |
| SCHEMBL24986864 | 0.68 | DRD4 (0.42) | DRD4DPP4CHRM4DRD3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |