Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.58 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.58 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.58 |
| ▸ | GLS | O94925 | 9/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141628 | 0.89 | MTOR (0.64) | MTORRPTORMLST8GLSCHRM4 | |
| SCHEMBL20141015 | 0.88 | MTOR (0.74) | MTORRPTORMLST8GLSGPR6 | |
| SCHEMBL20133716 | 0.87 | MTOR (0.66) | MTORRPTORMLST8GLSGPR6 | |
| SCHEMBL20133717 | 0.86 | MTOR (0.58) | MTORRPTORMLST8GLSGPR6 | |
| SCHEMBL20141512 | 0.85 | MTOR (0.59) | MTORRPTORMLST8GLSCHRM4 | |
| SCHEMBL20142476 | 0.81 | MTOR (0.59) | MTORRPTORMLST8GLS | |
| SCHEMBL21360368 | 0.80 | MTOR (0.69) | MTORRPTORMLST8GLS | |
| SCHEMBL20133757 | 0.80 | MTOR (0.62) | MTORRPTORMLST8GLS | |
| SCHEMBL20133755 | 0.79 | MTOR (0.54) | MTORRPTORMLST8GLS | |
| SCHEMBL22187991 | 0.78 | MTOR (0.57) | MTORRPTORMLST8GLSGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |