Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733471 | 0.84 | GAA (0.44) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1856696 | 0.84 | MEN1 (0.44) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27411185 | 0.83 | KDM4E (0.54) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2226009 | 0.83 | KMT2A (0.42) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL18339051 | 0.83 | AKR1C3 (0.53) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13917234 | 0.81 | KDM4E (0.50) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17262486 | 0.81 | GAA (0.42) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15323915 | 0.81 | KDM4E (0.50) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL762108 | 0.81 | KDM4E (0.50) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2226763 | 0.80 | AKR1C3 (0.61) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |