Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 1/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.71 |
| ▸ | CDK2 | P24941 | 4/20 | 0.71 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.68 |
| ▸ | TUBB | P07437 | 1/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.68 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.68 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481106 | 0.90 | CCNA2 (0.77) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4470938 | 0.90 | CDK5 (0.72) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20142440 | 0.90 | GSK3A (0.77) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4478062 | 0.90 | CCNA2 (0.87) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL6179397 | 0.88 | ZAP70 (0.65) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL25609561 | 0.88 | CCNA2 (0.67) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20142355 | 0.88 | CCNA2 (0.64) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20142382 | 0.88 | MEN1 (0.83) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20142430 | 0.87 | GSK3A (0.61) | ZAP70CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20142510 | 0.86 | ZAP70 (0.55) | ZAP70CCNA2CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |