SCHEMBL20142383

SCHEMBL20142383

Cc1ccc(C(=O)N2CCC[C@H](c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccc(NC(C)C)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489310 1.00 FASN (1.00) FASN
SCHEMBL4732891 0.98 FASN (0.95) FASN
SCHEMBL20156456 0.93 FASN (0.87) FASN
SCHEMBL18821667 0.92 FASN (0.86) FASN
SCHEMBL4782917 0.91 FASN (0.84) FASN
SCHEMBL4780785 0.91 FASN (0.83) FASN
SCHEMBL12686713 0.90 FASN (0.81) FASN
SCHEMBL29981429 0.90 FASN (1.00) FASN
SCHEMBL13277205 0.90 FASN (1.00) FASN
SCHEMBL4734847 0.89 FASN (0.80) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3538088-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V Biosciences, Inc. (US) 2019-09-18 EP disclosed
WO-2018089904-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2018-05-17 WO disclosed