Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 8/20 | 0.72 |
| ▸ | CDK2 | P24941 | 8/20 | 0.72 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.70 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25609586 | 0.89 | CCNA2 (0.72) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL4395888 | 0.88 | CDK5 (0.80) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL20142140 | 0.88 | CDK5 (0.69) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142395 | 0.87 | CCNA2 (0.77) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL20142498 | 0.85 | CCNA2 (0.52) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL7756155 | 0.84 | CDK5 (0.76) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL1248181 | 0.84 | CDK2 (1.00) | CCNA2CDK2CDK5CDK5R1CCNE1 | |
| SCHEMBL25220987 | 0.83 | MEN1 (0.78) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL20142855 | 0.83 | MEN1 (0.68) | CCNA2CDK2CDK5CDK5R1NPC1 | |
| SCHEMBL25609594 | 0.83 | MEN1 (0.78) | CCNA2CDK2CDK5CDK5R1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |