⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15191649 | 1.00 | — | — | |
| SCHEMBL14296324 | 1.00 | — | — | |
| SCHEMBL11173160 | 0.85 | — | — | |
| SCHEMBL14953179 | 0.81 | — | — | |
| SCHEMBL8987595 | 0.80 | — | — | |
| SCHEMBL11912323 | 0.80 | — | — | |
| SCHEMBL3008487 | 0.80 | — | — | |
| SCHEMBL9278753 | 0.80 | — | — | |
| SCHEMBL13105833 | 0.80 | — | — | |
| SCHEMBL15197997 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461817-B1 | POTASSIUM SALT OF BERAPROST | LUNG BIOTECHNOLOGY INC (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10710973-B2 | Method of producing beraprost | LUNG BIOTECHNOLOGY PBC (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190194156-A1 | METHOD OF PRODUCING BERAPROST | LUNG BIOTECHNOLOGY PBC (US) | 2019-06-27 | — | — | US | disclosed |
| US-10266509-B2 | Method of producing beraprost | LUNG BIOTECHNOLOGY PBC (US) | 2019-04-23 | — | — | US | disclosed |
| US-9969706-B2 | Method of producing beraprost | LUNG BIOTECHNOLOGY PBC (US) | 2018-05-15 | — | — | US | disclosed |