Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769335 | 0.81 | HRH3 (0.52) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15187055 | 0.79 | USP2 (0.47) | PAOXSIGMAR1GAACHRM2CHRM4 | |
| SCHEMBL15187056 | 0.79 | USP2 (0.47) | PAOXSIGMAR1GAACHRM2CHRM4 | |
| SCHEMBL438183 | 0.79 | PAOX (0.44) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL6657767 | 0.77 | PAOX (0.54) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL6663287 | 0.77 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20234244 | 0.77 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL14500306 | 0.77 | PAOX (0.54) | PAOXSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL15183552 | 0.77 | CHRM2 (0.40) | PAOXSIGMAR1GAACHRM2CHRM4 | |
| SCHEMBL15183550 | 0.77 | CHRM2 (0.40) | PAOXSIGMAR1GAACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968554-B2 | Modified drugs for use in liposomal nanoparticles | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2018-05-15 | — | — | US | disclosed |