⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216064 | 0.73 | — | — | |
| SCHEMBL6741364 | 0.73 | — | — | |
| SCHEMBL1751665 | 0.71 | — | — | |
| SCHEMBL594962 | 0.69 | — | — | |
| SCHEMBL7611491 | 0.67 | — | — | |
| SCHEMBL4805209 | 0.67 | — | — | |
| SCHEMBL28940928 | 0.67 | ACP1 (0.39) | — | |
| SCHEMBL695182 | 0.67 | — | — | |
| SCHEMBL28936805 | 0.67 | — | — | |
| SCHEMBL30537822 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073273-A1 | BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |
| EP-0264797-B1 | Benzodiazepines assay, tracers, immunogens and antibodies | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | claimed |
| US-5221629-A | Fluorescence polarization assay | ABBOTT LABORATORIES (US) | 1993-06-22 | — | — | US | claimed |
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | claimed |
| EP-0279308-A2 | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | claimed |
| EP-0264797-A2 | Benzodiazepines assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1988-04-27 | — | — | EP | claimed |
| EP-0201633-A2 | Substituted anilide compounds and their use | ABBOTT LABORATORIES (US) | 1986-11-20 | — | — | EP | claimed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | claimed |
| EP-0199042-A1 | Procainamide assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | claimed |
| EP-0194352-A2 | Salicylate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-09-17 | — | — | EP | claimed |
| WO-2011073273-A1 | BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |
| EP-0264797-B1 | Benzodiazepines assay, tracers, immunogens and antibodies | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |