Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314099 | 0.84 | KDM4E (0.32) | KDM4EHPGD | |
| SCHEMBL20626021 | 0.82 | KDM4E (0.39) | KDM4EHPGDPDE10ALMNANPC1 | |
| SCHEMBL20018392 | 0.82 | KDM4E (0.33) | KDM4EHPGDPDE10ALMNATSHR | |
| SCHEMBL19711803 | 0.79 | KDM4E (0.33) | KDM4EHPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL22100418 | 0.77 | TSHR (0.31) | KDM4EHPGDLMNATSHR | |
| SCHEMBL23047587 | 0.77 | KDM4E (0.38) | KDM4EHPGDLMNANPC1RAB9A | |
| SCHEMBL24440935 | 0.77 | KDM4E (0.34) | KDM4EHPGD | |
| SCHEMBL20215840 | 0.75 | KDM4E (0.33) | KDM4EHPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL14516233 | 0.73 | KDM4E (0.39) | KDM4EHPGDLMNANPC1RAB9A | |
| SCHEMBL31707307 | 0.72 | HPGD (0.40) | KDM4EHPGDNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2679616-B1 | Ultraviolet radiation absorbing polyethers | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-05-16 | — | — | EP | disclosed |