SCHEMBL20144429

SCHEMBL20144429

CSC(C)C(=O)NC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20392091 0.77
SCHEMBL22358623 0.76
SCHEMBL5847294 0.74
SCHEMBL11919896 0.72
SCHEMBL21787568 0.72
Hydrochloric Acid SCHEMBL29180799 0.72
SCHEMBL11271224 0.72
SCHEMBL24455406 0.71
SCHEMBL22788881 0.71 USP2 (0.31)
SCHEMBL22809886 0.70 CA12 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023201374-A1 COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2023-10-19 WO disclosed
WO-2023083343-A1 POLYCYCLIC COMPOUNDS AND METHODS THEREOF HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) 2023-05-19 WO disclosed
WO-2022133285-A1 MOLECULES AND METHODS RELATED TO TREATMNET OF DISORDERS ASSOCIATED WITH JAK-2 SIGNALING DYSFUNCTION ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2022-06-23 WO disclosed
WO-2021195406-A1 NEW THERAPEUTIC USES OF COMPOUNDS PROXIMAGEN, LLC (US) 2021-09-30 WO disclosed
WO-2020257733-A1 HISTONE DEMETHYLASE INHIBITORS FOR TREATING CANCERS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-12-24 WO disclosed
EP-3321257-A1 SUBSTITUTED 5-AMINOTHIENO[2,3-C]PYRIDAZINE-6-CARBOXAMIDE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 Vanderbilt University (US) 2018-05-16 EP disclosed