Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.71 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.71 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697650 | 1.00 | HCRTR1 (0.71) | HCRTR1HCRTR2MAP3K12CYP3A4 | |
| SCHEMBL18697754 | 0.88 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL20144723 | 0.88 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL16031707 | 0.83 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL16031710 | 0.83 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL16031481 | 0.83 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL20145056 | 0.83 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL20144759 | 0.83 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL16030515 | 0.83 | HCRTR1 (0.98) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL16030513 | 0.83 | HCRTR1 (0.98) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |