Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 15/20 | 1.00 |
| ▸ | HCRTR1 | O43613 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078132 | 1.00 | HCRTR2 (1.00) | HCRTR2HCRTR1MEN1TSHRKMT2A | |
| SCHEMBL16032973 | 1.00 | HCRTR2 (1.00) | HCRTR2HCRTR1MEN1TSHRKMT2A | |
| SCHEMBL16032435 | 1.00 | HCRTR2 (1.00) | HCRTR2HCRTR1MEN1TSHRKMT2A | |
| SCHEMBL20145060 | 0.91 | HCRTR2 (0.83) | HCRTR2HCRTR1 | |
| SCHEMBL16031595 | 0.86 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16030579 | 0.86 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16148647 | 0.86 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16078133 | 0.86 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16030577 | 0.86 | HCRTR1 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL16031146 | 0.84 | HCRTR2 (1.00) | HCRTR2HCRTR1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |