Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.68 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697814 | 1.00 | HCRTR1 (0.68) | HCRTR1HCRTR2CYP1A2GFER | |
| SCHEMBL18697649 | 0.93 | HCRTR1 (0.68) | HCRTR1HCRTR2GFER | |
| SCHEMBL20144733 | 0.93 | HCRTR1 (0.68) | HCRTR1HCRTR2GFER | |
| SCHEMBL20144816 | 0.88 | HCRTR2 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL18697815 | 0.88 | HCRTR2 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL20145061 | 0.83 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL20144780 | 0.83 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL20144846 | 0.83 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL16078104 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL16030866 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |