Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 17/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 16/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145044 | 1.00 | HCRTR2 (0.51) | HCRTR2HCRTR1MGLL | |
| SCHEMBL18697741 | 0.90 | HCRTR2 (0.51) | HCRTR2HCRTR1MGLL | |
| SCHEMBL20144800 | 0.90 | HCRTR2 (0.51) | HCRTR2HCRTR1MGLL | |
| SCHEMBL20144796 | 0.89 | HCRTR1 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL20145154 | 0.86 | HCRTR1 (0.64) | HCRTR2HCRTR1 | |
| SCHEMBL20144999 | 0.85 | HCRTR1 (0.57) | HCRTR2HCRTR1 | |
| SCHEMBL16148916 | 0.82 | HCRTR1 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL20145071 | 0.80 | HCRTR1 (0.54) | HCRTR2HCRTR1 | |
| SCHEMBL20144770 | 0.80 | HCRTR1 (0.54) | HCRTR2HCRTR1 | |
| SCHEMBL20144972 | 0.79 | HCRTR1 (0.53) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |