Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | CCNK | O75909 | 4/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK7 | P50613 | 4/20 | 0.38 |
| ▸ | CCNH | P51946 | 4/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144863 | 0.80 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL20144795 | 0.77 | HCRTR1 (0.72) | HCRTR1HCRTR2SSTR5GFER | |
| SCHEMBL20144965 | 0.77 | HCRTR1 (0.72) | HCRTR1HCRTR2SSTR5GFER | |
| SCHEMBL20144890 | 0.72 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL20145121 | 0.72 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL20145005 | 0.69 | HCRTR1 (0.69) | HCRTR1HCRTR2CCNKCCNA2CDK2 | |
| SCHEMBL18697666 | 0.69 | HCRTR1 (0.69) | HCRTR1HCRTR2CCNKCCNA2CDK2 | |
| SCHEMBL20144909 | 0.69 | HCRTR1 (0.70) | HCRTR1HCRTR2GFER | |
| SCHEMBL20144833 | 0.68 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL20144729 | 0.67 | HCRTR1 (0.46) | HCRTR1HCRTR2SSTR5EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |