Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 14/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16679963 | 0.86 | MAPK1 (0.73) | MAPK1 | |
| SCHEMBL16679154 | 0.81 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL16679532 | 0.81 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL16679138 | 0.81 | MAPK1 (0.72) | MAPK1 | |
| SCHEMBL16681263 | 0.81 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16679604 | 0.81 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16680328 | 0.81 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16680477 | 0.81 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16680479 | 0.81 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16679954 | 0.80 | MAPK1 (1.00) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |