Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16658357 | 0.88 | HPGD (0.69) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL17666331 | 0.85 | SMN1; SMN2 (0.70) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL1420642 | 0.84 | NR1H4 (0.62) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL16135739 | 0.83 | HPGD (0.56) | HPGDKMT2AALDH1A1HTTCYP3A4 | |
| SCHEMBL16982943 | 0.82 | HPGD (0.64) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL1500192 | 0.82 | HPGD (0.74) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL20145424 | 0.82 | KMT2A (0.74) | HPGDKMT2AALDH1A1HTTCYP2C19 | |
| SCHEMBL6430365 | 0.82 | HPGD (0.70) | HPGDKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL1032002 | 0.81 | MAPK1 (0.77) | HPGDKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL18378966 | 0.80 | KMT2A (0.49) | HPGDKMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |