Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690831 | 0.91 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL16690762 | 0.85 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL16679200 | 0.79 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16679243 | 0.79 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16684509 | 0.79 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL19053705 | 0.76 | MAPK1 (0.66) | MAPK1 | |
| SCHEMBL16680037 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16690761 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL16681202 | 0.75 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL20145461 | 0.75 | MAPK1 (0.72) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |