Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 18/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16680214 | 0.78 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL16679349 | 0.73 | PDGFRB (0.52) | MAPK1PDGFRBKDR | |
| SCHEMBL16679304 | 0.73 | MAPK1 (0.46) | MAPK1PDGFRBKDR | |
| SCHEMBL16680010 | 0.68 | PDGFRB (0.57) | MAPK1PDGFRBKDR | |
| SCHEMBL16680919 | 0.68 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL28257965 | 0.64 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL16679329 | 0.63 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL21264382 | 0.63 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL16680600 | 0.63 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL16680392 | 0.63 | MAPK1 (0.50) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |