Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 10/20 | 0.51 |
| ▸ | KDR | P35968 | 10/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145569 | 0.84 | PDGFRB (0.50) | PDGFRBKDRMAPK1NPC1POLB | |
| SCHEMBL16679059 | 0.83 | MAPK1 (0.64) | PDGFRBKDRMAPK1 | |
| SCHEMBL16679061 | 0.83 | MAPK1 (0.64) | PDGFRBKDRMAPK1 | |
| SCHEMBL20145456 | 0.77 | MAPK1 (0.71) | MAPK1 | |
| SCHEMBL16679573 | 0.76 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL16679571 | 0.76 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL16680010 | 0.70 | PDGFRB (0.57) | PDGFRBKDRMAPK1 | |
| SCHEMBL16679723 | 0.69 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL16690729 | 0.69 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL20145561 | 0.68 | MAPK1 (0.72) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063143-B1 | AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | disclosed |