Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079413 | 0.83 | AOC3 (0.46) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL9320598 | 0.82 | KCNA5 (0.46) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL14663983 | 0.82 | KCNA5 (0.46) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL8907881 | 0.82 | KCNA5 (0.46) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL10170136 | 0.78 | AOC3 (0.41) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL3326911 | 0.76 | AOC3 (0.44) | AOC3SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL28943433 | 0.76 | AOC3 (0.38) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL23033179 | 0.72 | AOC3 (0.40) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL15356024 | 0.72 | KCNA5 (0.50) | AOC3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL15940829 | 0.72 | ATM (0.37) | AOC3SLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |