Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138941 | 0.88 | EPHX2 (0.48) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL13139078 | 0.87 | EPHX2 (0.50) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL13138994 | 0.86 | KMT2A (0.55) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL13138970 | 0.86 | KMT2A (0.55) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL2010959 | 0.84 | EPHX2 (0.45) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL2015188 | 0.84 | EPHX2 (0.45) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL6919529 | 0.84 | EPHX2 (0.44) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL2012479 | 0.84 | EPHX2 (0.44) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL2012172 | 0.83 | HCRTR2 (0.47) | EPHX2HCRTR1HCRTR2KMT2AALOX15 | |
| SCHEMBL2012170 | 0.83 | HCRTR2 (0.47) | EPHX2HCRTR1HCRTR2KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |