Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463276 | 0.78 | — | — | |
| SCHEMBL31373438 | 0.78 | — | — | |
| SCHEMBL31373436 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL19926846 | 0.76 | KDM1A (0.57) | HTR2AANPEPKDM1AHRH1HTR2C | |
| SCHEMBL269188 | 0.76 | HTR2A (0.39) | HTR2AHRH1HTR2CIDO1 | |
| SCHEMBL22295673 | 0.76 | HTR2A (0.39) | HTR2AKDM1AHRH1HTR2CIDO1 | |
| SCHEMBL269189 | 0.76 | HTR2A (0.39) | HTR2AHRH1HTR2CIDO1 | |
| Hydrochloric Acid SCHEMBL22635715 | 0.74 | HTR2A (0.54) | HTR2AANPEPKDM1AHRH1HTR2C | |
| SCHEMBL15372611 | 0.72 | RET (0.37) | HTR2AHRH1HTR2CIDO1 | |
| SCHEMBL16904214 | 0.72 | HTR2A (0.36) | HTR2AANPEPKDM1AHRH1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3690038-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019142614-A1 | CONTAINER AND USE THEREOF | 国立研究開発法人産業技術総合研究所 | 2019-07-25 | — | — | WO | disclosed |
| EP-2907525-B1 | DIBENZOCYCLOOCTENE-COMPOUNDS FOR BIOORTHOGONAL REACTIONS | UNIV GEORGIA (US) | 2018-05-16 | — | — | EP | disclosed |