Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125973 | 0.88 | CYP3A4 (0.58) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20126009 | 0.81 | TSHR (0.58) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20126022 | 0.81 | TSHR (0.58) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20125918 | 0.81 | TSHR (0.58) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20126065 | 0.79 | TSHR (0.59) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20126033 | 0.79 | TSHR (0.56) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20126010 | 0.77 | TSHR (0.59) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20125980 | 0.76 | TSHR (0.62) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20125922 | 0.73 | CYP3A4 (0.61) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL20125971 | 0.72 | TSHR (0.63) | TSHRCYP3A4TDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321333-A1 | CURABLE COMPOSITION, CURABLE INK, ACCOMMODATING CONTAINER, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, CURED MATTER, AND ACRYLAMIDE COMPOUND | Ricoh Company Ltd. (JP) | 2018-05-16 | — | — | EP | disclosed |