Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 20/20 | 1.00 |
| ▸ | PDE2A | O00408 | 1/20 | 1.00 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061086 | 1.00 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| Pyrazole SCHEMBL28979341 | 0.84 | PDE3B (0.71) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL29407008 | 0.79 | PDE3B (0.65) | PDE3BPDE3APDE2A | |
| SCHEMBL10763338 | 0.78 | PDE3B (0.64) | PDE3BPDE3APDE2A | |
| SCHEMBL14493337 | 0.78 | BLM (0.70) | PDE3BPDE3APDE2A | |
| SCHEMBL10758208 | 0.77 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7880634 | 0.77 | PDE3B (0.77) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10758549 | 0.77 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10758507 | 0.77 | PDE3B (0.67) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10757077 | 0.77 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115716829-A | Quinolinoimidazolidone deuterated pyrazole compound and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-02-28 | — | — | CN | claimed |
| US-5567752-A | USEFUL IN CURABLE POLYORGANOSILOXANE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1996-10-22 | — | — | US | claimed |
| US-5487948-A | Bis(bis-silylalkyl) dicarboxylates as adhesion promoters and compositions containing them | GENERAL ELECTRIC COMPANY (US) | 1996-01-30 | — | — | US | claimed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | claimed |
| CN-86102747-A | The preparation method of imidazoquinoline antithombogehic cardiotonic agents | — | 1987-02-04 | — | — | CN | claimed |
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024149378-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | 上海超阳药业有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-115716829-A | Quinolinoimidazolidone deuterated pyrazole compound and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115716829-A | Quinolinoimidazolidone deuterated pyrazole compound and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115716829-A | Quinolinoimidazolidone deuterated pyrazole compound and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-1807440-B1 | NOVOBIOCIN ANALOGUES AS ANTICANCER AGENTS | UNIV KANSAS (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-2438078-B1 | NOVOBIOCIN ANALOGUES HAVING MODIFIED SUGAR MOIETIES | UNIV KANSAS (US) | 2017-10-25 | — | — | EP | disclosed |
| CN-1016175-B | Imidazoquinoline antithrombin cardiotonic agents | BRISTOL MYERS CO (US) | 1992-04-08 | — | — | CN | disclosed |
| EP-0426180-A2 | Imidazo[4,5-b] quinolinyloxyalkanoic acid amides with enhanced water solubility | Bristol-Myers Squibb Company (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4943573-A | ENZYME INHIBITORS, CARDIOTONIC, ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4668686-A | 1,3-DIHYDRO-2H-IMIDAZO/4,5-B/QUINOLINE-2-ONES | BRISTOL-MYERS COMPANY (US) | 1987-05-26 | — | — | US | disclosed |