Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.54 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.54 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.54 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133783 | 0.89 | MTOR (0.60) | MTORRPTORMLST8MALT1TRPA1 | |
| SCHEMBL20133581 | 0.87 | MTOR (0.62) | MTORRPTORMLST8MALT1TRPA1 | |
| SCHEMBL20149900 | 0.86 | MTOR (0.75) | MTORRPTORMLST8 | |
| SCHEMBL20149904 | 0.85 | MTOR (0.52) | MTORRPTORMLST8MALT1 | |
| SCHEMBL20133576 | 0.85 | MTOR (0.75) | MTORRPTORMLST8MALT1TRPA1 | |
| SCHEMBL20133849 | 0.84 | MTOR (0.57) | MTORRPTORMLST8MALT1 | |
| SCHEMBL20133577 | 0.83 | MALT1 (0.53) | MTORRPTORMLST8MALT1TRPV1 | |
| SCHEMBL20133684 | 0.83 | MTOR (0.65) | MTORRPTORMLST8MALT1TRPA1 | |
| SCHEMBL21340096 | 0.83 | MTOR (0.65) | MTORRPTORMLST8MALT1TRPA1 | |
| SCHEMBL20141044 | 0.83 | MTOR (0.65) | MTORRPTORMLST8MALT1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |