Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.61 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.61 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133539 | 0.90 | MTOR (0.67) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140834 | 0.90 | MTOR (0.67) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20133714 | 0.90 | MTOR (0.67) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20133769 | 0.90 | MTOR (0.67) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20133767 | 0.90 | MTOR (0.67) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20149900 | 0.90 | MTOR (0.75) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20133682 | 0.80 | MTOR (0.82) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20129720 | 0.79 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20129726 | 0.79 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20129724 | 0.79 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |