⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459849 | 0.84 | — | — | |
| SCHEMBL19089959 | 0.74 | — | — | |
| SCHEMBL23768628 | 0.71 | — | — | |
| SCHEMBL18633921 | 0.61 | — | — | |
| SCHEMBL19068110 | 0.58 | — | — | |
| SCHEMBL21074522 | 0.57 | — | — | |
| SCHEMBL21649875 | 0.57 | — | — | |
| SCHEMBL19068077 | 0.57 | — | — | |
| SCHEMBL20362655 | 0.57 | — | — | |
| SCHEMBL20362669 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273240-B2 | Cortistatin analogues, syntheses, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-30 | — | — | US | disclosed |
| US-20180134725-A1 | CORTISTATIN ANALOGUES, SYNTHESES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-05-17 | — | — | US | disclosed |