SCHEMBL20152153

SCHEMBL20152153

c1ccc(-c2nc(-c3ccc(-n4c5ccccc5c5c6c7ccccc7n(-c7cccc(-c8nc(-c9ccc%10ccccc%10c9)c9ccccc9n8)c7)c6ccc54)cc3)nc3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
WHR1 P49842 1/20 0.37
ABCG2 Q9UNQ0 5/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34
USP2 O75604 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
GBA1 P04062 1/20 0.34
ADORA2A P29274 2/20 0.33
VDR P11473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152202 1.00 ATM (0.44) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL20152154 0.97 MEN1 (0.43) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL19654051 0.97 ATM (0.41) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL20152155 0.96 MEN1 (0.41) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL20152159 0.95 MEN1 (0.48) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL19653993 0.94 MEN1 (0.41) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL20152144 0.94 ATM (0.49) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL19654010 0.94 ATM (0.43) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL23370463 0.93 ATM (0.48) ATMMEN1KMT2AWHR1ABCG2
SCHEMBL19654001 0.93 ATM (0.45) ATMMEN1KMT2AWHR1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885MEN1 4244/4885KMT2A 3996/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885MEN1 4244/4885KMT2A 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.