SCHEMBL20152206

SCHEMBL20152206

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccc(-c8nc(-c9ccccc9)c9ccccc9n8)cc7)c6ccc54)cc3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
NUDT1 P36639 3/20 0.40
ADORA2A P29274 1/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ABCG2 Q9UNQ0 3/20 0.39
WHR1 P49842 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ACP1 P24666 2/20 0.38
GAA P10253 1/20 0.38
PDE5A O76074 2/20 0.37
LMNA P02545 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152161 0.99 ATM (0.56) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL23370458 0.97 ATM (0.55) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL20315811 0.97 MEN1 (0.55) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL19654002 0.97 ATM (0.55) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL20152169 0.96 ATM (0.54) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL19654003 0.96 MEN1 (0.53) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL19654005 0.96 MEN1 (0.53) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL20152181 0.95 MEN1 (0.52) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL20226351 0.94 ATM (0.51) ATMMEN1KMT2ANUDT1ADORA2A
SCHEMBL20152138 0.93 ATM (0.50) ATMMEN1KMT2ANUDT1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885MEN1 4244/4885KMT2A 3996/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885MEN1 4244/4885KMT2A 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.