Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152955 | 0.85 | BACE1 (0.54) | BACE1MAPTABCG2MEN1KMT2A | |
| SCHEMBL7687335 | 0.84 | MAPT (0.46) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7687333 | 0.84 | MAPT (0.46) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7681007 | 0.82 | MAPT (0.44) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7681012 | 0.82 | MAPT (0.44) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6798674 | 0.82 | KDM4E (0.45) | MAPTLMNAKMT2AKDM4EHPGD | |
| SCHEMBL6798679 | 0.82 | KDM4E (0.45) | MAPTLMNAKMT2AKDM4EHPGD | |
| SCHEMBL26601267 | 0.81 | MAPT (0.67) | BACE1MAPTLMNAMEN1KMT2A | |
| SCHEMBL20152901 | 0.80 | MAPT (0.50) | BACE1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1820391 | 0.78 | CHRNA7 (0.64) | BACE1MAPTLMNAIAPPTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |