⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20962702 | 0.84 | USP2 (0.46) | — | |
| SCHEMBL23126209 | 0.83 | USP2 (0.41) | — | |
| SCHEMBL25870804 | 0.83 | — | — | |
| SCHEMBL10128466 | 0.82 | CYP2D6 (0.39) | — | |
| SCHEMBL27352594 | 0.81 | CYP2D6 (0.31) | — | |
| SCHEMBL20962686 | 0.81 | — | — | |
| SCHEMBL20153180 | 0.81 | — | — | |
| SCHEMBL23365994 | 0.81 | USP2 (0.32) | — | |
| SCHEMBL19300389 | 0.78 | HRH3 (0.34) | — | |
| SCHEMBL27276166 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133200-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC. | 2018-05-17 | — | — | US | disclosed |