Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15618802 | 0.86 | CHRM1 (0.47) | CHRM1CHRM4 | |
| SCHEMBL15618629 | 0.81 | CHRM1 (0.52) | CHRM1CHRM4HRH3 | |
| SCHEMBL15618631 | 0.81 | CHRM1 (0.52) | CHRM1CHRM4HRH3 | |
| SCHEMBL15618785 | 0.80 | CHRM4 (0.38) | CHRM1CHRM4HRH3 | |
| SCHEMBL20292096 | 0.75 | NPC1 (0.36) | CHRM1CHRM4HRH3 | |
| SCHEMBL17506708 | 0.73 | CHRM1 (0.44) | CHRM1CHRM4HRH3 | |
| SCHEMBL17506709 | 0.73 | CHRM1 (0.44) | CHRM1CHRM4HRH3 | |
| SCHEMBL20291992 | 0.73 | HRH3 (0.40) | CHRM4HRH3 | |
| SCHEMBL20292094 | 0.71 | HRH3 (0.39) | CHRM4HRH3 | |
| SCHEMBL23849701 | 0.70 | HRH3 (0.39) | CHRM1CHRM4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975890-B2 | Bicyclic AZA compounds as muscarinic M1 receptor antagonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2018-05-22 | — | — | US | claimed |