Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21291218 | 0.81 | EPHX1 (0.44) | CNR1CNR2FAAHEPHX1 | |
| SCHEMBL20652302 | 0.80 | CNR2 (0.53) | CNR1CNR2FAAH | |
| SCHEMBL23696755 | 0.80 | EPHX1 (0.47) | CNR1CNR2FAAHEPHX1 | |
| SCHEMBL23613227 | 0.79 | CNR1 (0.56) | CNR1CNR2FAAH | |
| SCHEMBL25973013 | 0.78 | EPHX1 (0.50) | CNR1CNR2FAAHEPHX1 | |
| SCHEMBL25110744 | 0.78 | EPHX1 (0.50) | CNR1CNR2FAAHEPHX1 | |
| SCHEMBL18625376 | 0.77 | CYP2D6 (0.41) | CNR1CNR2EPHX1 | |
| SCHEMBL18410790 | 0.75 | CNR1 (0.46) | CNR1FAAH | |
| SCHEMBL24764125 | 0.72 | CYP2D6 (0.37) | EPHX1 | |
| SCHEMBL21291261 | 0.72 | CYP2D6 (0.37) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133337-A1 | CALICHEAMICIN CONSTRUCTS AND METHODS OF USE | ABBVIE STEMCENTRX LLC (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133337-A1 | CALICHEAMICIN CONSTRUCTS AND METHODS OF USE | CALD1, CALR, CLSPN | CNR1 3295/4885CNR2 3778/4885FAAH 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.