SCHEMBL20154276

SCHEMBL20154276

CCSCc1cc(C)cc(CSC(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.35
POLB P06746 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138190 0.86 POLB (0.38) EPHX1POLBALDH1A1
SCHEMBL21374500 0.84
SCHEMBL21241482 0.82 POLB (0.41) EPHX1POLBALDH1A1
SCHEMBL24448701 0.76 TYR (0.34)
SCHEMBL10178671 0.75 USP2 (0.34) POLBALDH1A1
SCHEMBL21374150 0.70 TYR (0.33)
SCHEMBL20614519 0.69 TYR (0.32)
SCHEMBL21374152 0.68 TYR (0.30)
SCHEMBL13169184 0.67 IDO1 (0.47) EPHX1ALDH1A1
SCHEMBL10204873 0.67 TAAR1 (0.53) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089648-A2 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2018-05-17 WO disclosed