Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.60 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155235 | 0.93 | BRD4 (0.69) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20155350 | 0.92 | BRD4 (0.65) | BRD4 | |
| SCHEMBL20155288 | 0.81 | BRD4 (0.89) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20155665 | 0.80 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20155285 | 0.79 | BRD4 (0.67) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20155264 | 0.78 | BRD4 (0.53) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL15069613 | 0.75 | BRD4 (1.00) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL19931189 | 0.75 | BRD4 (0.59) | BRD4 | |
| SCHEMBL20155671 | 0.74 | BRD4 (0.53) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20154974 | 0.74 | BRD4 (0.88) | BRD4BRD2ADORA2BTSPOEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |